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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605e16c8197dc69f38238b4f302be5c18f765a39f47cb0a1b01479222f70a51f' 
  AND token = 'kN3PXe1O9z7bmZwsVURdKgkez2VBMHWfbgQc4tpMe+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}