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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '555fece8b60bae6200800c4c4cfdf49e60ec8621009b5c125e98ed1c0bbe0c46' 
  AND token = 'V2Sm48lWn6ehYHzGJ1EOcLy9xO6J59VdztP0ouwm6D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}