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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b2cf9f274a1e3c5889abfdeb21442a2db4ff245d0f5aafbf816a18a9e0f3b2' 
  AND token = 'XY9MvX5p9oWql/ixzvawCjrJCyCN6xJwcxjZbl/7xL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}