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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e11d9b87ee1deb83243f1ff862f1d118405e64654f7d747aaba0d0310cc3e16' 
  AND token = 'Gz4D3BHP0UlL6BaIPMg1V0PBIaygIawAXfgkgEHR8bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}