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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60fe097cf0130f62f45e64b73f1a8645c47349e4323223e3732f9fd7d18e6448' 
  AND token = 'RdeECc5xVlSuIDmGJtJmkFMskyli6jRkQ0QZ0UkXDoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}