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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbd9ac5e3f6d353485a1e4b81faeae1de301123bcd3abd731658c56a3b49714' 
  AND token = 'plw/jYUGI9siAb0ySJizCFvJtUeT8XUT7Vbw4pQwUTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}