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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27acf8b7f60c859274496533ce0f7cf6946aed5c1563ddcfc859b13c6c52869' 
  AND token = 'Vfc0Iv2PHRUzvsAWVJTfv7Hw8UVw17BEcyW7QEiPceQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}