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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4771bdcf441cebef7c6966f8f853d8d1f961ec9cafcf876e91aeb2fa0d063458' 
  AND token = 'f7Eahv4Yxq7WhUzyuV+a5IJpaoL3bjrOQRsh3vBR0iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}