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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd93457e39ba581f66d9b72000bd7a553066bef7acc6324da051548c2f634ad48' 
  AND token = 'HRDQfdfPYIgdnti2iICiFgc8PtTP7rO32GXQNRHuvfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}