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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1be8d3ea91e14ed00c05f0c53ba63fca27405fc0801fe4f887c75afde2fa0f' 
  AND token = '9AEys6xFZiUbDwFZGY2WfMfV6U1k4u/l59YumrPYdig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}