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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6a7b0e7f653f27d439c48efbfd1028a57c6e7ad0f1ad97d0dea9a0500bf591' 
  AND token = 'aAE62i10FFsZEbHo2a5hyWIaFEZUs8n6MrZ+JlAH0pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}