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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ada5914036d8e54b8204c19cc4f21650ebb2a4bcdf2420a9c52f23463d7cd4a0' 
  AND token = '78jXmTavshJV/HbWsS6o9OU8dMbR6a2Bfcn0iuUhTgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}