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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c00673ede2b374b8c4670f078435efd21e980d17163a93cdeefd9ac2325f4f' 
  AND token = 'OVT2+zmOJbrKM0oZea4LyOzWb4gr5JBQdiu8G9037KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}