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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b45726d9f1c0feb495235c1af9786134481cc92c0b29500c8d91a9e57fe05d8' 
  AND token = 'IbTbUYoSDy9jMa8UffabZME8ah8Cp6SlnoqYP2+x2kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}