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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4680e17c2610c7c2f0f3e3ba967ab177fda5668113c8b74c09b212168c9c609d' 
  AND token = 'JjgoLrQe2B7PecUwEefQjuUoEaQi68FyGPpEo6opsNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}