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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1785d8ee1e1fb25d493859997d4bad865465e83fc2d2cabf8bd87056326f4837' 
  AND token = 'n2fWQa+Zu25X+RBTBwCU/c7AQLHN1rLs/DAcWoG4IaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}