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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd488f0f61a0daf33557ff78c0fbffeef0ac3c8c19152b872b0c5e60d4f879306' 
  AND token = 'VPwM3eIpjsLfWVLmP9h5SK3GE8NSFQIMQ+Ex44J5GLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}