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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae1512c51b26ee64b685254973b77294ecc7fa06f52f82d5c3028dc9d0ad273' 
  AND token = 'SK1WaZIiKvko8+WXTPS5WjrPhz2KZtjyjXhF0PpD43w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}