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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a3a7e2a4e31ccb9c9d4abe0f020ebef4dbd42563b92f7b39efbbcdae5ac780' 
  AND token = '6/Qs0ud7K+azjVNwsD3N//5EG9ppuqfuSvulmCiQ2eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}