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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d49083010db674daea87754b3acc7085819ca9c5b81736516504ce951c37fa1' 
  AND token = 'hkNpw6Y9SWoH78mQH3nsHMP8uwA93VcTgtEcw5/nFi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}