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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef56dd1d4e3f7dd9caf86f40613d26657a76baa9c465dfbf91bbc12d5282c18' 
  AND token = 't1jLivQIjQWkXyaYE6XoWBvP0IksS5bdgJguXpRVaJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}