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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed0fa8e9ef86e0d8f23fbcf3cfecd47fffcd62723dec295df2a99c62c101d02' 
  AND token = 'uAm2Z2MtEDdocYIojpR1cs9+98R6xSQjLxwKBji6FFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}