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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5cb378bd3f9db0b933a53f081cb79906789af7c5f62842b02b9b2687300f0a1' 
  AND token = 'Legqnlp30o77WIHmhd3XLOol9hFe0S0t11h3/MWYK48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}