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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757e31bc4e031683267cc9b7cf6ca758d7d663b34227e451f3dfe0896fb96f5c' 
  AND token = '/LBMv9x3eXFd2Sho0QCynQQYWYcLxlY3M0ObGaq7lVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}