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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e74eda23e9caf25e1dc98b3cebe06fc176308f5861bb02ae98c50f745e2f4fc' 
  AND token = 'SsFKNg4whGZUPNaF4AFgep2uAksUr30yoN3YVRANM8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}