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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca255d54f0fddddd2bd23512e019b14817fe5fe89058a2338b49f30cac7c51d' 
  AND token = '+D7Sl4xy1i3x8JiMvmXTzI1QDdmeM37gVZOVfJ5GACY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}