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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40eaa4f6daedf08945e21d2b01b324d04b8b75bfa40c0300ad5ca34c2ab23bc1' 
  AND token = 'V4gbcGDY6aa6H0IySd51eBJUmXW+8x8FRv+PgV8xcUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}