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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad8ddcb31c839aa9d5d89f2c81f281135bdecfcee2cb0723201e36bdd3f7f79' 
  AND token = 'yd8l+o3+AjVXKJ7z8vkb1lCopnRZ5kZhZg7OOpJ5wBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}