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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72793d33b7c83f22deaa5205f5f9d492963a670115da47420a3cbb4bf2fb5da1' 
  AND token = 'fewHLnPZR0SdZ/UOIIcgY5OmUlkd+vXgL9dMwyYqLnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}