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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e15d031ee182f7445a49484515f51c5106c855ffc85062005cf60126c94bf2' 
  AND token = '1NjEiD5Czyl1ACV4TO/BdSUVODNClkAAXsmikNv94d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}