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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9c03f2c66fc63d282ef4fe59b4ebb366203b068f5254bf11021f4c8ebf7458' 
  AND token = 'NcRriKB1I6cg7rC29ZKQ5pjr7T8S4SV7Z6UY/yq1ZqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}