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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63025e086c0f5496f32ae87bc0236074a378170ecdbde54c46b7b40857f481b9' 
  AND token = 'x42oDjL34Z+0oPU3ShW2apwg4QpSj0FiOO4Gz0yIzh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}