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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eab9164d6a8faa9fa8c7406b311e93e81604aa2370bde0a98b42f80dca05fb9' 
  AND token = 'r2hJOEvLRCIYf6U+Q86qOQgqq43CGHDJj8fn0LVa4fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}