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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d4881c145143e976a87fa1a0e8d875fc6e306f712560b266039ca2f8715a6e' 
  AND token = 'hHIMvirc+Mg4c24mOOYAQmantK4DJWvY9es2EH2HzqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}