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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7ba7ded43987d2367cf9a4117293ed8c2892477572f6d0b2996b541cedb907' 
  AND token = 'dRGjAkeGT34c0B1V7c4MC+MzYKczhF1m+xYmj46MxEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}