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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33dce228b0a3b8fa510263af2d3fe6fc23952d71f05ef8375a3a6877737a7291' 
  AND token = 'MfeNA0ZVT9KvsYhCZ8VcGQ4m3eMQ06G9kHcLLK6RF/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}