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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537ca4929a84518077db2407306341f264e43866a4362f831c763a8271f94365' 
  AND token = 'ONnG0TjZ4pnrPb+q3h3GIE964n037DxNNlNweX8XnL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}