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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cb410a59f764cdd581efbe0b11c72a220c12d462d5969b1a33feee219ac991' 
  AND token = 'O1u+/5ksP57gTLTx1/sOm01Iw1smPPHYaj8/o4HheJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}