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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03d2cfdd71b09c018bb6da22da97b56f6176afdb2647e755bbfc7cc63f41e72' 
  AND token = 'JO/VaowoE0zab5HwkqZpYFdV0rZs354stuKf8gG7r9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}