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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d60a3734c28df6cbc2f09754a9c668a9523bc6e6f3fc94546ef397d7d8376d8' 
  AND token = '+/xzzf7q9K0Gx/xtbLWnCWyFL0WT8E9DnO2vjqzBNIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}