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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8c6c42185025f246144b0e4879f6e25ab0025b6d7d3ef822f221b38a14007d' 
  AND token = 'FcApY1vfLwpF2404rcW3ANToMnOpQsLCUj5yH9bGm5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}