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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1610c25b1106b1c3950fc11fe7b64a4bc807861b86bc30e2dd95de3923730f' 
  AND token = 'c0/52ieBR2d7OFbFCDhH6GE2WGz8Ehmvf/ZeUc7NoPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}