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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2ff6e6b7d70f21618f9acb368aa4d1d6edca849515a2dace8ffc11261bf740' 
  AND token = 'prrzNx5VAg4cagtyvcPdVx/QIH7a0lsXHByhQ/6ocYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}