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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0db654c5093cb4af58621bba5540faadec77004c30bac1844b6f86d4cd0fb91' 
  AND token = 'sFflaIORQIf9e3CRw6c+kvt+pUr/hUWGDHBi5kQtRRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}