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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3dcbeef4ebf4a308d86a96382b7d2556e067a8a3a97bb4a0daa484a7555136' 
  AND token = 'eTYeorLhWsSUYOT8FeyORzPFjJ84i6GicGOYyFptPxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}