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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9160ab9dbbb0b1c04e766a1ec06219151a18a0820e449f85cad355c1b4d953' 
  AND token = 'UPJTZ8Kzc7AFtA4AJjTMOQt1wqtEqiNpij1ui69oUtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}