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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be67e4e31a9ce596039d04c0d144e22689302930b3cfcf67f206316e2e35ed39' 
  AND token = 'gvm+BcSI8Jq/dLs4dAd2EVrNIYWc8+BAyqgSNvXmP8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}