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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56557e0291b2d11f277589fd685f4dce5f0cc6fa724e8d1012ae3c87602725a4' 
  AND token = 'oXVTi3M0oqiSpp41uOvsDpnepXQbPPfyIa3r62smsp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}