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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6670a1c6aec60af568d32eef2980a5dd91172e52f2f48470749303f23a3c8203' 
  AND token = 'D2A31hRONioz7Pu276LRiAmfeqIvOz2qdtAZacgKp0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}