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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9c2ef953e1882e00325374701243178053ff0eacf1c87c07e5fe69a23b27e8' 
  AND token = 'eqf4Nrp58zuvJP9iCm93gu6igRf4Ope/8wsZ1iUBt0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}